[Disturbed glucose tolerance and diabetes mellitus in the relatives of patients with the juvenile form of diabetes mellitus].

A total of 200 relatives of patients with a juvenile form of diabetes mellitus were examined. The standard oral glucose tolerance test (GTT) was used with a simultaneous determination (during the test) of immunoreactive insulin (IRI) level. GTT was found to be deranged in 39% of the patients investigated (doubtful results--in 24%, latent diabetes--in 8%, manifest diabetes--in 7%). The incidence of diabetes mellitus had a direct correlation with age and weight of the patients. During the GTT IRI was found to be high in 40.8% of the cases, and torpid type of the insulinemia curve was noted in 2% of the cases only.