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青少年型糖尿病患者亲属的糖耐量异常及糖尿病

[Disturbed glucose tolerance and diabetes mellitus in the relatives of patients with the juvenile form of diabetes mellitus].

作者信息

Tursunov B, Mazovetskiĭ A G, Zavadskiĭ P S

出版信息

Probl Endokrinol (Mosk). 1978 Sep-Oct;24(5):13-6.

PMID:704551
Abstract

A total of 200 relatives of patients with a juvenile form of diabetes mellitus were examined. The standard oral glucose tolerance test (GTT) was used with a simultaneous determination (during the test) of immunoreactive insulin (IRI) level. GTT was found to be deranged in 39% of the patients investigated (doubtful results--in 24%, latent diabetes--in 8%, manifest diabetes--in 7%). The incidence of diabetes mellitus had a direct correlation with age and weight of the patients. During the GTT IRI was found to be high in 40.8% of the cases, and torpid type of the insulinemia curve was noted in 2% of the cases only.

摘要

共检查了200名青少年型糖尿病患者的亲属。采用标准口服葡萄糖耐量试验(GTT),并在试验期间同时测定免疫反应性胰岛素(IRI)水平。在接受调查的患者中,发现39%的患者GTT异常(可疑结果——24%,潜伏性糖尿病——8%,显性糖尿病——7%)。糖尿病的发病率与患者的年龄和体重直接相关。在GTT期间,40.8%的病例中IRI较高,仅2%的病例中发现胰岛素血症曲线呈迟缓型。

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