Natarov V V, Zhurova M V, Kharag G I, Iankelevich D E
Probl Endokrinol (Mosk). 1978 Sep-Oct;24(5):25-9.
In examination of patients with thyrotoxicosis, aged from 14 to 24 years, there was revealed a reduction of the activity of the mediatory link of the sympathico-adrenal ssystem without any connection with age, the severity and duration of the disease, and also with the efficacy of drug therapy. The functional test with insulin in patients with thyrotoxicosis permitted to detect definite reserve possibilities of the adrenergic regulation intensified with increased duration of the disease and with advance of the patient's age, but not with increased severity of the disease. The insulin test offered a possibility of assessing the sympathico-adrenal system reactivity in cases of different degree of the disease compensation.
在对年龄在14至24岁的甲状腺毒症患者进行检查时发现,交感 - 肾上腺系统中介环节的活性降低,且与年龄、疾病的严重程度和持续时间以及药物治疗效果均无关联。甲状腺毒症患者的胰岛素功能试验能够检测到随着疾病持续时间的延长和患者年龄的增长而增强的肾上腺素能调节的一定储备可能性,但与疾病严重程度的增加无关。胰岛素试验为评估不同疾病代偿程度情况下交感 - 肾上腺系统的反应性提供了可能。