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[去势及丙酸睾酮对雄性大鼠不同脑区3H-去甲肾上腺素代谢的影响]

[Effect of castration and testosterone propionate on 3H-noradrenaline metabolism in different brain structures in male rats].

作者信息

Bekhtereva E P

出版信息

Probl Endokrinol (Mosk). 1978 Sep-Oct;24(5):56-9.

PMID:704559
Abstract

Experimental results demonstrated that castration in male rats led to the changes in catecholamine metabolism in various regions of the brian. In particular there is an acceleration of labeled noradrenalin- disappearance (3H-noradrenaline) from the limbic system of the hypothalamus formations. Testosterone propionate restored the initial level of 3H-noradrenaline in the mentioned structures of the brain. The data obtained indicated that adrenorecption of the rynecephalo-hypothalamic complex took part in the central regulation of the gonadotropic function of the hypophysis.

摘要

实验结果表明,雄性大鼠去势会导致大脑各区域儿茶酚胺代谢的变化。特别是,下丘脑边缘系统结构中标记去甲肾上腺素(3H-去甲肾上腺素)的消失加速。丙酸睾酮可使上述大脑结构中3H-去甲肾上腺素的初始水平恢复。所获得的数据表明,嗅脑-下丘脑复合体的肾上腺素受体参与了垂体促性腺功能的中枢调节。

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