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输精管结扎术能降低前列腺肿瘤的发病率吗?

Can vasectomy reduce the incidence of prostatic tumor?

作者信息

Sheth A R, Panse G T

出版信息

Med Hypotheses. 1982 Mar;8(3):237-41. doi: 10.1016/0306-9877(82)90118-9.

DOI:10.1016/0306-9877(82)90118-9
PMID:7045601
Abstract

Results from our laboratory have revealed that seminal plasma concentration of acid phosphatase, maltase, prolactin, citric acid, zinc and magnesium which are the secretory products of the prostate gland, decreased significantly in vasectomized men compared to those in controls namely normal fertile men. Further, it was observed that the decrease in prostatic function was not related to the time since vasectomy. Considering these two facts together, we propose that vasectomy may lead to decrease in the incidence of prostatic tumors - a disease that claims nearly 22,000 lives each year in the United States alone.

摘要

我们实验室的研究结果显示,前列腺分泌的酸性磷酸酶、麦芽糖酶、催乳素、柠檬酸、锌和镁的精浆浓度,与对照组即正常生育男性相比,输精管结扎男性显著降低。此外,观察到前列腺功能的下降与输精管结扎后的时间无关。综合考虑这两个事实,我们认为输精管结扎可能会导致前列腺肿瘤发病率降低——仅在美国,这种疾病每年就夺去近22000人的生命。

相似文献

1
Can vasectomy reduce the incidence of prostatic tumor?输精管结扎术能降低前列腺肿瘤的发病率吗?
Med Hypotheses. 1982 Mar;8(3):237-41. doi: 10.1016/0306-9877(82)90118-9.
2
Long-term effects of vasectomy on prostatic function in men.输精管结扎术对男性前列腺功能的长期影响。
J Reprod Fertil. 1980 Mar;58(2):289-93. doi: 10.1530/jrf.0.0580289.
3
Vasectomy and vasovasostomy have no effect on seminal plasma zinc concentrations.输精管切除术和输精管吻合术对精浆锌浓度没有影响。
J Urol. 1987 Feb;137(2):228-9. doi: 10.1016/s0022-5347(17)43961-9.
4
Endocrine and accessory sex organ function after vasectomy and vasovasostomy.
Arch Androl. 1981 Sep;7(2):187-91. doi: 10.3109/01485018108999306.
5
[Changes of free amino acids in seminal plasma with vasectomy and reanastomosis of the vas deferens (author's transl)].输精管结扎及输精管再吻合术后精浆中游离氨基酸的变化(作者译)
Nihon Funin Gakkai Zasshi. 1981 Apr;26(2):12-6.
6
Seminal plasma concentration of glycerylphosphorylcholine before and after vasectomy and vas reanastomosis.输精管结扎术及输精管再吻合术前、后精浆中甘油磷酸胆碱的浓度
Fertil Steril. 1979 Dec;32(6):685-6. doi: 10.1016/s0015-0282(16)44420-1.
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Polyamines and other accessory sex gland secretions in human seminal plasma 8 years after vasectomy.输精管结扎术后8年人精浆中的多胺及其他附属性腺分泌物
J Reprod Fertil. 1989 Sep;87(1):39-45. doi: 10.1530/jrf.0.0870039.
8
Nature of the residual alpha-1,4-glucosidase activity in the seminal plasma of vasectomized men.输精管结扎男性精液中残余α-1,4-葡萄糖苷酶活性的性质
Enzyme. 1985;34(1):33-8. doi: 10.1159/000469357.
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Laminin and aminoterminal propeptide of type III procollagen in seminal plasma from fertile and vasectomized men.来自生育能力正常和输精管结扎男性的精浆中的层粘连蛋白和III型前胶原氨基末端前肽。
Andrologia. 1993 Jul-Aug;25(4):217-21. doi: 10.1111/j.1439-0272.1993.tb02712.x.
10
The long-term influence of vasectomy on prostatic volume and morphology in man.
Prostate. 1988;13(1):57-67. doi: 10.1002/pros.2990130107.

引用本文的文献

1
Vasectomy and prostate cancer risk: a pooled of cohort studies and Mendelian randomization analysis.输精管切除术与前列腺癌风险:队列研究与孟德尔随机化分析的汇总
BMC Cancer. 2025 Feb 24;25(1):332. doi: 10.1186/s12885-025-13750-8.
2
Association between vasectomy and risk of prostate cancer: a meta-analysis.输精管切除术与前列腺癌风险之间的关联:一项荟萃分析。
Prostate Cancer Prostatic Dis. 2021 Dec;24(4):962-975. doi: 10.1038/s41391-021-00368-7. Epub 2021 Apr 29.
3
Vasectomy, cigarette smoking, and age at first sexual intercourse as risk factors for prostate cancer in middle-aged men.
输精管切除术、吸烟及首次性交年龄作为中年男性患前列腺癌的风险因素
Br J Cancer. 1988 Mar;57(3):326-31. doi: 10.1038/bjc.1988.74.