Demoulin L, Bassleer J, Boisvert H, Desmecht M, Moens R, Nyabenda J, Portaels F, Truffot C, Viallier J, Viallier G
Pathol Biol (Paris). 1982 Feb;30(2):102-5.
An M. intracellulare, rough strain (serotype 7) has been isolated from sputum of a sixty-year old patients. This patient was a political prisoner in Germany between 1942-1945 and had contracted pulmonary tuberculosis with the cavity in the upper lobe of the right lung. A strain of mycobacterium susceptible to antituberculous drugs was isolated from his sputum in 1973. Since 1979, the isolation of M. Intracellulare has been accompanied by clinical signs of pulmonary mycobacteriosis, i.e. persistence of the cavity in spite of antituberculous treatments reapparition of cough with sputum, general weakness. Intradermo-reaction with specific sensitin gives a strong positive reaction, contrasting with a weak reaction with PPD tuberculin. As the antibiogram of the strain shows a susceptibility to cotrimoxazole and erythromycin, the patient underwent a therapy with the combination sulfamethaxozale-trimethoprime and erythromycin, for 4 months. At the end of this treatment, he seems to have recovered completely. The radiological aspect of the lungs remains unchanged. Although the source of contamination remains unknown, one thinks on the basis of bibliographica data, that it can be found in human beings, or seldom in animals (a pig, a bird) or in nature (a pond).
从一名60岁患者的痰液中分离出一株胞内分枝杆菌粗糙菌株（血清型7）。该患者在1942年至1945年期间是德国的一名政治犯，曾患肺结核，右肺上叶有空洞。1973年从其痰液中分离出一株对抗结核药物敏感的分枝杆菌菌株。自1979年以来，胞内分枝杆菌的分离一直伴随着肺分枝杆菌病的临床症状，即尽管进行了抗结核治疗，空洞仍持续存在，再次出现咳嗽伴咳痰、全身虚弱。用特异性变应素进行皮内反应呈强阳性反应，与结核菌素纯蛋白衍生物（PPD）的弱阳性反应形成对比。由于该菌株的抗菌谱显示对复方新诺明和红霉素敏感，该患者接受了磺胺甲恶唑-甲氧苄啶与红霉素联合治疗4个月。治疗结束时，他似乎已完全康复。肺部的放射学表现保持不变。尽管污染源仍然不明，但根据文献资料推测，可能存在于人类中，或很少见于动物（猪、鸟）或自然界（池塘）中。
