Ohman U
Am J Surg. 1982 Jun;143(6):742-7. doi: 10.1016/0002-9610(82)90050-2.
Over a 30 year interval (1950 to 1979), 1,061 patients with colorectal carcinoma were seen; 148 presented with bowel obstruction and in this retrospective study were compared with those having nonobstructive tumors. The age and sex distribution did not differ between the groups. The curability rate was 53 percent, versus 72 percent for nonobstructed patients; the 5 year survival rate was 16 percent overall and 31 percent in curable cases, versus 37 and 50 percent for elective patients, respectively. Survival within tumor stages did not differ between the groups; the difference in outcome was mainly a result of obstructed patients having fewer stage A and more stage C lesions. Most right-sided growths were primarily resected, while the left-sided growths were mainly treated with staged resection. Operative mortality for curable patients was 8 percent, not different from the 7 percent rate in elective patients. The 5 year survival rate was 19 percent after primary and 35 percent after staged resection. It was concluded that patients with bowel obstruction secondary to colorectal carcinoma have low curability and survival rates, primarily because of advanced disease at the time of diagnosis and treatment.
在30年期间（1950年至1979年），共诊治了1061例结直肠癌患者；其中148例出现肠梗阻，在这项回顾性研究中，将他们与患有非梗阻性肿瘤的患者进行了比较。两组患者的年龄和性别分布无差异。梗阻组的治愈率为53%，非梗阻组为72%；总体5年生存率为16%，可治愈病例为31%，而择期手术患者分别为37%和50%。两组患者在肿瘤分期内的生存率无差异；结果差异主要是由于梗阻患者中A期病变较少而C期病变较多。大多数右侧肿瘤主要行根治性切除，而左侧肿瘤主要采用分期切除治疗。可治愈患者的手术死亡率为8%，与择期手术患者7%的死亡率无差异。一期切除术后5年生存率为19%，分期切除术后为35%。结论是，结直肠癌继发肠梗阻患者的治愈率和生存率较低，主要原因是诊断和治疗时疾病已处于晚期。
