Kaverina N V, Berdiaev S Iu, Mel'nikova T S
Biull Eksp Biol Med. 1982 May;93(5):68-72.
To reveal latent cardiac pathology in alcoholic patients'--the adaptation mechanisms adjusting the heart to the exercise test were quantitatively evaluated. The computer-made histograms of the cardiac rhythm of 30 practically healthy humans and 24 alcoholic patients showed before, during and after the exercise test that the variation range of the R-R interval was drastically decreased in alcoholic patients as compared to normal, while their mode was shifted towards shorter cardiointervals and had an increased amplitude. When the alcoholic patients were exposed to the exercise tests the shifts of the cardiointerval parameters in them were sharply different from those observed in the healthy subjects and after the test was over, the initial cardiac rhythm parameters failed to reappear within more than 3 min. Nonachlazin treatment of alcoholic cardiomyopathy increased the exercise tolerance estimated on the basis of the computer-processed cardiac rhythm, contributing to the reappearance of the normal clinical picture in the patients.
为揭示酒精性心肌病患者潜在的心脏病变——对心脏适应运动试验的调节机制进行了定量评估。通过计算机绘制的30名健康人和24名酒精性心肌病患者在运动试验前、试验期间和试验后的心律直方图显示，与正常人相比，酒精性心肌病患者的R-R间期变化范围显著减小，而其众数向更短的心电间期偏移且幅度增大。当酒精性心肌病患者进行运动试验时，他们的心电间期参数变化与健康受试者明显不同，试验结束后，初始心律参数在3分钟以上未能恢复。非那嗪治疗酒精性心肌病可提高基于计算机处理心律评估的运动耐力，促使患者恢复正常临床表现。
