Michetti F, Cocchia D
Cell Tissue Res. 1982;223(3):575-82. doi: 10.1007/BF00218477.
The presence of an S-100-like immunoreactivity was investigated in the planarian Dugesia gonocephala. By microcomplement fixation assay, measurable amounts of S-100-like immunoreactive material (0.11 microgram/mg soluble protein) were detected in planarian high-speed supernatants. The index of immunological dissimilarity between ox S-100 and planarian S-100-like immunoreactive material was higher than that previously calculated between ox S-100 and all the vertebrates tested. By the immunohistochemical PAP method, S-100-like immunoreactivity was only detectable in the cilia of the epidermal cells. Although the biological meaning of S-100-like immunoreactivity in planarian remains to be clarified, the present data introduce new perspectives into the investigation of S-100.
在三角涡虫（Dugesia gonocephala）中研究了S-100样免疫反应性的存在情况。通过微量补体固定试验，在涡虫高速上清液中检测到了可测量量的S-100样免疫反应性物质（0.11微克/毫克可溶性蛋白）。牛S-100与涡虫S-100样免疫反应性物质之间的免疫差异指数高于先前计算的牛S-100与所有测试脊椎动物之间的免疫差异指数。通过免疫组织化学PAP方法，仅在表皮细胞的纤毛中可检测到S-100样免疫反应性。尽管涡虫中S-100样免疫反应性的生物学意义仍有待阐明，但目前的数据为S-100的研究引入了新的视角。
