Peerbooms P G, Marian A, Verweij J J, MacLaren D M
Infect Immun. 1982 Jun;36(3):1246-8. doi: 10.1128/iai.36.3.1246-1248.1982.
Two experimental mouse models were tested for their suitability in measuring urinary virulence of Proteus mirabilis. In the first model, the kidney-infecting dose and lethal dose were measured. In the second model, the kinetics of the numbers of bacteria in the kidneys and other organs of the mouse were monitored for 13 h after injection.
对两种实验小鼠模型进行了测试,以评估它们在测量奇异变形杆菌尿液毒力方面的适用性。在第一个模型中,测量了肾脏感染剂量和致死剂量。在第二个模型中,在注射后13小时监测小鼠肾脏和其他器官中细菌数量的动态变化。