克雅氏病的预防措施。

Precautions for Creutzfeldt-Jakob disease.

作者信息

Jarvis W R

出版信息

Infect Control. 1982 May-Jun;3(3):238-9. doi: 10.1017/s0195941700056162.

DOI:10.1017/s0195941700056162

Abstract

Creutzfeldt-Jakob disease (CJD) is a rapidly progressive, fatal disease of the central nervous system. Premortem diagnosis may or may not be conclusive. Because the etiologic agent is virulent, definition of necessary precautions for medical staff associated with such patients is needed. Transmission of CJD in animals has been found to occur after inoculation with brain, spinal cord, liver, kidney, lung, and lymph node tissues in diminishing frequency. Effective methods of sterilization and disinfection for the etiologic agent are unknown. Thus, personnel associated with supposed-CJD patients should take precautions not unlike needle precautions for hepatitis B patients. A list of guidelines is given.

摘要

克雅氏病（CJD）是一种中枢神经系统迅速进展的致命疾病。生前诊断可能明确，也可能不明确。由于病原体具有传染性，因此需要明确与这类患者接触的医护人员的必要预防措施。已发现，用大脑、脊髓、肝脏、肾脏、肺和淋巴结组织接种动物后，克雅氏病会在动物间传播，传播频率逐渐降低。目前尚不清楚针对该病原体的有效灭菌和消毒方法。因此，与疑似克雅氏病患者接触的人员应采取与乙肝患者针头预防措施类似的预防措施。以下是一份指南清单。