α-子宫蛋白在人子宫内膜中的定位

Localization of alpha-uterine protein in human endometrium.

作者信息

Horne C H, Paterson W F, Sutcliffe R G

出版信息

J Reprod Fertil. 1982 Jul;65(2):447-50. doi: 10.1530/jrf.0.0650447.

DOI:10.1530/jrf.0.0650447

Abstract

Immunoperoxidase staining was used to investigate the origin of human alpha-uterine protein (AUP). Specific staining was observed in the glandular epithelium of the endometrium during the secretory phase of the menstrual cycle and during pregnancy, and in a patient on an oestrogen-progestagen contraceptive pill. The pattern of staining strongly suggests that AUP is secreted into the uterine lumen. The location and concentration of AUP in the uterus may explain the relative concentrations of AUP in amniotic fluid and maternal serum.

摘要

采用免疫过氧化物酶染色法研究人α-子宫蛋白（AUP）的来源。在月经周期的分泌期、妊娠期以及服用雌激素-孕激素避孕药的患者子宫内膜腺上皮中观察到特异性染色。染色模式强烈提示AUP分泌至子宫腔。AUP在子宫中的位置和浓度可能解释了羊水和母血中AUP的相对浓度。

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