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儿童脾切除术的并发症(作者译)

[Complications of splenectomy in childhood (author's transl)].

作者信息

Holschneider A M, Kricz-Klimeck H, Strasser B, Däumling S, Belohradsky B H

出版信息

Z Kinderchir. 1982 Apr;35(4):130-9. doi: 10.1055/s-2008-1059923.

Abstract

161 children followed up postoperatively following splenectomy, 29% had spherocytosis, 14% Hodgkin's disease, 12% traumatic rupture of the spleen, 11% portal hypertension and 7% idiopathic thrombocytopenia. Postoperatively a slight wound infection occurred in 5% of the children, while complications were seen in 2% which could be interpreted as directly caused by the operation; in 23 patients, however, (i.e. 15%), severely infections occurred such as pneumonia, meningitis and sepsis. The lethality rate of the infected children was 31.8%. Postoperatively we determined the leucocyte count, thrombocytes and erythrocyte count, the immunoglobulins IgG, IgA, IgM and IgE, the serum concentrations of the complement components C3, C4 and the serum proteins alpha 1-antitrypsin and transferrin. The data obtained were compared with the corresponding data reported in the literature.

摘要

161名儿童在脾切除术后接受随访,其中29%患有球形红细胞增多症,14%患有霍奇金病,12%为脾外伤性破裂,11%为门静脉高压,7%为特发性血小板减少症。术后,5%的儿童出现轻微伤口感染,2%出现可被认为是手术直接导致的并发症;然而,有23名患者(即15%)发生了严重感染,如肺炎、脑膜炎和败血症。感染儿童的致死率为31.8%。术后我们测定了白细胞计数、血小板和红细胞计数、免疫球蛋白IgG、IgA、IgM和IgE、补体成分C3、C4的血清浓度以及血清蛋白α1-抗胰蛋白酶和转铁蛋白。将获得的数据与文献中报道的相应数据进行了比较。

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