Roffman M, Silbermann M, Mendes D G
Acta Orthop Scand. 1982 Aug;53(4):513-9. doi: 10.3109/17453678208992250.
The idea of utilizing bone grafts during hip arthroplasty has been discussed in the literature and clinical successes have been indicated. These communications, however, did not relate to long-term results. Thus, to date, we still lack sufficient understanding as to the fate of bone grafts when they are coated with methylmethacrylate. In order to elucidate the above issue further an experimental study has recently been initiated in an attempt to provide answers to the following questions: a) do bone grafts remain viable when they are held in place with methylmethacrylate bone cement? and b) do such grafts retain their osteogenic potential? In the present study osteotomies were made in the femora of dogs and cortico-cancellous strips of autogenous bone were placed around the osteotomy site. The grafts were then surrounded by polymethylmethacrylate bone cement. Mechanical examination and morphological studies, performed 3, 6 and 10 months following surgery, revealed the elaboration of fibro-osseous union. Our present findings tend to indicate that bone grafts, even if they are covered with methylmethacrylate bone cement, still retain their viability as well as their osteogenic potential.
髋关节置换术中使用骨移植的想法已在文献中进行了讨论，并显示出临床成功案例。然而，这些报道并未涉及长期结果。因此，迄今为止，我们对骨移植被甲基丙烯酸甲酯涂层覆盖后的命运仍缺乏足够的了解。为了进一步阐明上述问题，最近启动了一项实验研究，试图回答以下问题：a）当骨移植用甲基丙烯酸甲酯骨水泥固定在位时，它们是否仍能保持活力？b）这样的移植骨是否保留其成骨潜力？在本研究中，在狗的股骨上进行截骨，并将自体骨的皮质-松质条带放置在截骨部位周围。然后用聚甲基丙烯酸甲酯骨水泥包裹移植骨。在手术后3、6和10个月进行的力学检查和形态学研究显示形成了纤维-骨联合。我们目前的研究结果倾向于表明，骨移植即使被甲基丙烯酸甲酯骨水泥覆盖，仍保留其活力以及成骨潜力。
