Valenti P, Antonini G, Fanelli M R, Orsi N, Antonini E
Antimicrob Agents Chemother. 1982 May;21(5):840-1. doi: 10.1128/AAC.21.5.840.
Ovotransferrin immobilized by covalent linkage to Sepharose 4B showed a bacteriostatic effect towards Escherichia coli similar to that of free ovotransferrin. The growth of the bacteria, after exposure to the gel-bound ovotransferrin and its removal, depended on the length of exposure. The results suggest that the antibacterial activity of transferrin is not due simply to the removal of iron from the medium.
通过共价连接固定在琼脂糖4B上的卵转铁蛋白对大肠杆菌显示出与游离卵转铁蛋白相似的抑菌作用。细菌在接触凝胶结合的卵转铁蛋白并将其去除后,其生长取决于接触时间的长短。结果表明,转铁蛋白的抗菌活性并非仅仅归因于从培养基中去除铁。