Takagi S, Sakata H, Yoshida T, Den K, Fujii T K, Amemiya H, Tomita M
Prostaglandins. 1978 May;15(5):913-9. doi: 10.1016/0090-6980(78)90159-4.
ONO-802 was used in the form of vaginal suppositories for the termination of early pregnancy in 63 healthy volunteers. Fifty-four (86%) of the 63 cases had complete abortions and remaining 9 (14%) had incomplete abortions. One (1.6%) of the 63 cases complained of nausea and vomiting, and 3 (4.8%) complained of headaches. No other side effects were observed. These results suggest that ONO-802 is acceptable in the form of vaginal suppositories for the termination of early pregnancy.
ONO - 802以阴道栓剂的形式用于63名健康志愿者的早期妊娠终止。63例中有54例(86%)完全流产,其余9例(14%)流产不全。63例中有1例(1.6%)出现恶心呕吐,3例(4.8%)出现头痛。未观察到其他副作用。这些结果表明,ONO - 802以阴道栓剂的形式用于早期妊娠终止是可以接受的。