• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

接受卵磷脂治疗的阿尔茨海默病患者血浆中游离胆碱水平的波动:初步观察。

Fluctuations of free choline levels in plasma of Alzheimer patients receiving lecithin: preliminary observations.

作者信息

Chuaqui P, Levy R

出版信息

Br J Psychiatry. 1982 May;140:464-9. doi: 10.1192/bjp.140.5.464.

DOI:10.1192/bjp.140.5.464
PMID:7049290
Abstract

Plasmas of 12 patients currently taking part in a double-blind trial of lecithin in senile or presenile dementia of Alzheimer type were analysed for plasma choline levels at fixed intervals during lecithin treatment. The values were not maintained at a constant level and showed a decline after one or two months of treatment, often followed by a subsequent rise. Possible explanations for this observation are given, and its significance to the treatment of dementia discussed.

摘要

对12名目前正在参与一项关于卵磷脂治疗阿尔茨海默型老年性或早老性痴呆双盲试验的患者血浆,在卵磷脂治疗期间按固定间隔分析其血浆胆碱水平。这些数值并未维持在恒定水平,在治疗一两个月后呈现下降,随后常常又上升。文中给出了对这一观察结果的可能解释,并讨论了其对痴呆治疗的意义。

相似文献

1
Fluctuations of free choline levels in plasma of Alzheimer patients receiving lecithin: preliminary observations.接受卵磷脂治疗的阿尔茨海默病患者血浆中游离胆碱水平的波动:初步观察。
Br J Psychiatry. 1982 May;140:464-9. doi: 10.1192/bjp.140.5.464.
2
A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease.一项关于高剂量卵磷脂治疗阿尔茨海默病的双盲、安慰剂对照试验。
J Neurol Neurosurg Psychiatry. 1985 Aug;48(8):736-42. doi: 10.1136/jnnp.48.8.736.
3
Double blind study of lecithin in patients with Alzheimer's disease.卵磷脂治疗阿尔茨海默病患者的双盲研究。
Can J Psychiatry. 1981 Oct;26(6):426-8. doi: 10.1177/070674378102600608.
4
Alzheimer disease: lack of effect of lecithin treatment for 3 months.阿尔茨海默病:卵磷脂治疗3个月无效。
Neurology. 1981 Dec;31(12):1552-4. doi: 10.1212/wnl.31.12.1552.
5
Lecithin does not affect EEG spectral analysis or P300 in Alzheimer disease.
Neurology. 1982 Nov;32(11):1260-6. doi: 10.1212/wnl.32.11.1260.
6
A dose-ranging study of lecithin in the treatment of primary degenerative dementia (Alzheimer disease).
J Clin Psychopharmacol. 1982 Aug;2(4):281-5.
7
Piracetam plus lecithin trials in senile dementia of the Alzheimer type.吡拉西坦加卵磷脂治疗阿尔茨海默型老年痴呆症的试验。
Ann N Y Acad Sci. 1985;444:478-81. doi: 10.1111/j.1749-6632.1985.tb37616.x.
8
No effect from double-blind trial of physostigmine and lecithin in Alzheimer disease.
Ann Neurol. 1983 Feb;13(2):210-2. doi: 10.1002/ana.410130220.
9
Lecithin in the treatment of Alzheimer's disease.卵磷脂在阿尔茨海默病治疗中的应用
Arch Neurol. 1983 Aug;40(8):527-8. doi: 10.1001/archneur.1983.04210070067022.
10
Combination therapy with lecithin and ergoloid mesylates for Alzheimer's disease.卵磷脂与甲磺酸双氢麦角碱联合治疗阿尔茨海默病。
J Clin Psychiatry. 1986 May;47(5):249-51.