Kaiser W, Otten G, Köhnlein H E, Kitzinger H
Fortschr Med. 1982 Jul 1;100(25):1213-6.
Macro- and histopathological examinations were performed on 200 Wistar rats of both sexes which had been intraperitoneally treated with either Brauns resorbable surgical glove powder or Bio-sorb surgical glove powder; control animals were injected with talcum powder. Talcum resulted in the well known foreign body granuloma along with adhesions. The amylaceous powders induced an initial inflammatory reaction with a subsequent non-reactive interval and thereafter solitary foreign body granulomas were formed. After terminating the experiment (12 weeks), no adhesions could be detected in animals treated with starch containing powder. A resorption of the powder was assumed in that the number of powder crystals was greatly reduced by the end of the experiment. The granulomas which developed after the 12th week were regarded as resorption granulomas. The development of adhesions was minimal with both types of amylaceous powder.
对200只经腹腔注射布劳恩可吸收手术手套粉或生物可吸收手术手套粉的雌雄Wistar大鼠进行了大体和组织病理学检查;对照动物注射滑石粉。滑石粉导致了众所周知的异物肉芽肿以及粘连。淀粉类粉末引发了最初的炎症反应,随后有一个无反应期,此后形成了孤立的异物肉芽肿。实验结束(12周)后,在用含淀粉粉末处理的动物中未检测到粘连。假定粉末发生了吸收,因为到实验结束时粉末晶体的数量大大减少。第12周后形成的肉芽肿被视为吸收性肉芽肿。两种淀粉类粉末导致的粘连发展都很轻微。