Suppr超能文献

牛的染色体显带研究。

Chromosome banding studies in cattle.

作者信息

Logue D N

出版信息

Res Vet Sci. 1978 Jul;25(1):1-6.

PMID:705033
Abstract

A recent advance in the field of cytogenetics has been the ability to stain differentially specific areas or bands on the fixed chromosome. In terms of clinical and paraclinical work C- and G-bands have been of most value to date in allowing precise identification of chromosome homologues even in species such as cattle, where the vast majority of chromosomes are of a similar morphology. These methods have allowed at the gross level of the chromosome the precise identification of a number of Robertsonian translocations and certain aneuploids. In this study 1/29 Robertsonian translocations were found in three separate breeds. Also a 14/20 and a 6/16 Robertsonian translocation were identified as was a 61XXY sterile bull. In the future these techniques will allow the identification of as yet unidentified anomalies in cattle such as reciprocal translocations and paracentric inversions. Since many anomalies have been correlated with such clinical problems as early embryonic death, abortion, congenital anomalies and reduced reproductive efficiency in the mammalia, it is important to use cytogenetics as an additional laboratory aid in such investigations.

摘要

细胞遗传学领域最近的一项进展是能够对固定染色体上的特定区域或带进行差异染色。就临床和临床旁工作而言,C带和G带在精确识别染色体同源物方面具有最大价值,即使在牛等物种中也是如此,在这些物种中绝大多数染色体具有相似的形态。这些方法在染色体的总体水平上,使得能够精确识别一些罗伯逊易位和某些非整倍体。在本研究中,在三个不同品种中发现了1/29的罗伯逊易位。还鉴定出了一个14/20和一个6/16的罗伯逊易位,以及一头61XXY的不育公牛。未来,这些技术将能够识别牛中尚未发现的异常情况,如相互易位和臂内倒位。由于许多异常情况与哺乳动物早期胚胎死亡、流产、先天性异常和繁殖效率降低等临床问题相关,因此在这类研究中使用细胞遗传学作为额外的实验室辅助手段非常重要。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验