Bastide M, Jouvert S, Bastide J M
Pathol Biol (Paris). 1982 Jun;30(6):458-62.
Imidazoles (econazole, miconazole, ketoconazole, isoconazole, 10(-3) M.) used to treat intact cells and sphaeroplasts of Candida albicans caused small lesions in the cell wall, but none or minor less in the cytoplasmic membrane. On the other hand, clotrimazole, in the same conditions, caused important lesions in the cytoplasmic membrane and none on the cell wall. Miconazole, econazole and isoconazole inhibited the release of sphaeroplasts from treated intact yeast cells.
咪唑类药物（益康唑、咪康唑、酮康唑、异康唑，10⁻³M）用于处理白色念珠菌的完整细胞和原生质球时，会使细胞壁出现小损伤，但对细胞质膜无损伤或损伤较小。另一方面，在相同条件下，克霉唑会使细胞质膜出现严重损伤，而对细胞壁无损伤。咪康唑、益康唑和异康唑会抑制经处理的完整酵母细胞释放原生质球。
