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移植前及移植当天输血:对尸体移植物存活的影响。

Blood transfusions before and on the day of transplantation: effects on cadaver graft survival.

作者信息

Feduska N J, Amend W J, Vincenti F, Duca R, Salvatierra O

出版信息

Transplant Proc. 1982 Jun;14(2):302-4.

PMID:7051470
Abstract

Pre-BTs significantly improve the survival rate for first cadaver transplants, by a mechanism that remains obscure. The maximal influence is seen with smaller numbers of pre-BTs (1-5 units), but is also observed with larger numbers of pre-BTs. The possible beneficial influence of Tx-BTs on graft survival is not proven, and if it exists at all is not nearly as striking as the effect seen with pre-BTs. Tx-BTs neither potentiate nor nullify the benefit of pre-BTs on graft survival. It is therefore recommended that pre-BTs in smaller numbers, such as 1-5 units, be administered to candidates for first cadaver transplants to increase the probability of a successful outcome. Tx-BTs should be utilized when clinically indicated but not with the expectation that they will necessarily improve graft survival.

摘要

术前输血显著提高了首次尸体移植的存活率,但其机制尚不清楚。少量术前输血(1 - 5单位)时影响最大,但大量术前输血时也有此现象。移植时输血对移植物存活的可能有益影响尚未得到证实,即便存在,也远不如术前输血的效果显著。移植时输血既不能增强也不能消除术前输血对移植物存活的益处。因此,建议对首次尸体移植候选者给予少量(如1 - 5单位)术前输血,以提高成功移植的概率。临床有指征时应使用移植时输血,但不能期望其必然会提高移植物存活率。

相似文献

1
Blood transfusions before and on the day of transplantation: effects on cadaver graft survival.移植前及移植当天输血:对尸体移植物存活的影响。
Transplant Proc. 1982 Jun;14(2):302-4.
2
Kidney graft survival: role of blood transfusions and lymphocytotoxic antibodies.肾移植存活:输血及淋巴细胞毒性抗体的作用。
Clin Nephrol. 1982 Aug;18(2):69-73.
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Annual trends and triple therapy--1991-2000.1991 - 2000年的年度趋势与三联疗法
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Two random transfusions before primary renal transplantation--four years' experience from a single center.原发性肾移植前两次随机输血——来自单一中心的四年经验
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引用本文的文献

1
Transfusion support of the transplant patient.移植患者的输血支持。
Can Fam Physician. 1988 Nov;34:2503-8.