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恶性间皮瘤的化疗;CAMEO。

Chemotherapy for malignant mesothelioma; CAMEO.

作者信息

Jett J R, Eagan R T

出版信息

Am J Clin Oncol. 1982 Aug;5(4):429-31. doi: 10.1097/00000421-198208000-00014.

DOI:10.1097/00000421-198208000-00014
PMID:7051806
Abstract

Twelve patients with a tissue diagnosis of malignant mesothelioma were treated with combination chemotherapy (CAMEO) every 4-5 weeks, with or without hemithoracic radiation. Mean survival from the time of tissue diagnosis an start of protocol treatment was 15.7 and 12.6 months, respectively. Median survival from the time of tissue diagnosis and start of protocol treatment was 11 and 6.5 months, respectively. Two patients were long-term survivors (32 and 45 months), one of whom is alive without evidence of recurrent disease. Toxicity from this regimen was moderate.

摘要

12例经组织学诊断为恶性间皮瘤的患者每4至5周接受联合化疗(CAMEO方案),部分患者接受或未接受半胸放疗。从组织学诊断至开始方案治疗的平均生存期分别为15.7个月和12.6个月。从组织学诊断至开始方案治疗的中位生存期分别为11个月和6.5个月。2例患者为长期生存者(分别为32个月和45个月),其中1例仍存活,无疾病复发迹象。该治疗方案的毒性为中度。

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引用本文的文献

1
Malignant mesothelioma of the pleura: a study of 52 treated and 64 untreated patients.胸膜恶性间皮瘤:52例接受治疗患者和64例未接受治疗患者的研究。
Thorax. 1984 Apr;39(4):255-9. doi: 10.1136/thx.39.4.255.
2
Chemotherapy in malignant mesothelioma: a review.恶性间皮瘤的化疗:综述
Cancer Chemother Pharmacol. 1991;28(5):319-30. doi: 10.1007/BF00685684.