Meyer C H
Appl Neurophysiol. 1981;44(5-6):345-54. doi: 10.1159/000102217.
In 14 patients with parkinsonism a unilateral ablation at the lower border of the ventrolateral thalamus relieved tremor and rigidity in the contralateral arm but not in the ipsilateral arm. Voluntary movement improved in both arms for three single-handed tasks, each involving the proximal and distal parts of the limb. For one task (a ballistic drawing movement) the postoperative change in one arm was correlated with that in the other arm. The lesion also improved repetitive voluntary movement of the fingers, but only in the contralateral hand.
在14例帕金森病患者中,在丘脑腹外侧下缘进行单侧毁损术可缓解对侧手臂的震颤和强直,但同侧手臂无此效果。对于三项单手任务,每项任务都涉及肢体的近端和远端部分,双臂的自主运动均得到改善。对于一项任务(弹道式绘图运动),术后一侧手臂的变化与另一侧手臂的变化相关。该毁损术还改善了手指的重复性自主运动,但仅对侧手部有改善。