有证据表明大鼠外周髓鞘不包含大鼠脊髓蛋白（RSCP-PN）。

Evidence that rat peripheral myelin does not contain the rat spinal cord protein (RSCP-PN).

作者信息

Weir K G, MacPherson C F

出版信息

Neurosci Lett. 1980 Jan;16(1):97-101. doi: 10.1016/0304-3940(80)90108-1.

Abstract

Rat spinal cord protein (SCP) from peripheral nerves (RSCP-PN) was not detected in purified rat peripheral nerve myelin by sodium dodecyl sulfate (SDS)-polyacrylamide slab gel electrophoresis or by immunodiffusion analyses using an anti-rat SCP in peripheral nerve (RSCP-PN) serum. The slab gel electrophoretic analyses also revealed that RSCP-PN has an appreciably lower molecular size than the component of rat peripheral myelin that is identified as P2 by its molecular size of 13,600 daltons. Thus, RSCP-PN and rat P2 are unrelated proteins.

摘要

通过十二烷基硫酸钠（SDS）-聚丙烯酰胺平板凝胶电泳或使用抗大鼠外周神经脊髓蛋白（RSCP-PN）血清进行免疫扩散分析，在纯化的大鼠外周神经髓鞘中未检测到来自外周神经的大鼠脊髓蛋白（SCP）。平板凝胶电泳分析还显示，RSCP-PN的分子大小明显低于大鼠外周髓鞘中被鉴定为P2的成分，其分子大小为13,600道尔顿。因此，RSCP-PN和大鼠P2是不相关的蛋白质。