非洲爪蟾双神经支配视顶盖中光纤投射分离为眼特异性条带。

Segregation of optic fibre projections into eye-specific bands in dually innervated tecta in Xenopus.

作者信息

Straznicky C, Tay D, Hiscock J

出版信息

Neurosci Lett. 1980 Sep;19(2):131-6. doi: 10.1016/0304-3940(80)90183-4.

Abstract

The restoration of the retinotectal projections following metamorphic bilateral optic nerve sections was studied in Xenopus 20 weeks after operation, using [3H]proline autoradiography and electrophysiological mapping. Optic fibre projections from each eye to both tecta segregated into eye-specific termination bands with some overlap at the borders. The bands were arranged rostrocaudally in the tecta such that each eye had an alternating representation. Despite the segregation of the optic fibres, each eye had a complete visual (retinal) projection with the normal nasotemporal and dorsoventral polarities of the visual field maintained. The results suggest competition for preferred terminal sites between the two sets of optic fibres in dually innervated tecta.

摘要

在非洲爪蟾身上，利用[3H]脯氨酸放射自显影术和电生理图谱技术，研究了变态期双侧视神经切断术后20周视网膜-顶盖投射的恢复情况。来自每只眼睛到双侧顶盖的视神经纤维投射分离成眼特异性终末带，在边界处有一些重叠。这些带在顶盖中按前后顺序排列，使得每只眼睛都有交替的表征。尽管视神经纤维分离，但每只眼睛都有完整的视觉（视网膜）投射，保持了视野正常的鼻颞侧和背腹侧极性。结果表明，在双重支配的顶盖中，两组视神经纤维之间存在对优选终末位点的竞争。