Tay D, Straznicky C
Neurosci Lett. 1980 Jun;18(2):137-42. doi: 10.1016/0304-3940(80)90316-x.
Following unilateral optic nerve section in Xenopus tadpoles and toadlets, the reformation of visual pathways and retinotectal projections was analyzed using [3H]proline autoradiography. Bilateral retinotectal projections were found in 61% of the animals operated on between stages 42 and 58. In these animals, the projections were established through multiple aberrant pathways which included the oculomotor nerve, the trigeminal nerve and the posterior commissure. In contrast, in animals with optic nerve section at stage 62 or after metamorphosis, the regenerated optic fibres arrived at the contralateral and ipsilateral tecta through normal visual pathways.
在非洲爪蟾蝌蚪和幼蟾进行单侧视神经切断术后，使用[3H]脯氨酸放射自显影术分析视觉通路和视网膜-脑顶盖投射的重塑。在42至58期接受手术的动物中，61%发现有双侧视网膜-脑顶盖投射。在这些动物中，投射通过多种异常通路建立，包括动眼神经、三叉神经和后连合。相比之下，在62期或变态后进行视神经切断的动物中，再生的视神经纤维通过正常视觉通路到达对侧和同侧脑顶盖。
