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心肌梗死后患者和匹配的对照受试者对情绪应激(问答式访谈)的心血管反应。

Cardiovascular responses to emotional stress (quiz interview) in post-myocardial infarction patients and matched control subjects.

作者信息

Sime W E, Buell J C, Eliot R S

出版信息

J Human Stress. 1980 Sep;6(3):39-46. doi: 10.1080/0097840X.1980.9936097.

Abstract

In this investigation, 30 male post-myocardial infarction patients and 30 male control subjects matched according to age and occupation were given a 12-minute tape-recorded stress quiz described by Schiffer et al. Cardiovascular responses (electrocardiogram, heart rate, systolic, blood pressure, and diastolic blood pressure) to emotional stimuli were monitored in a laboratory setting at rest before the quiz and at two-minute intervals during the quiz. Heart rate and blood pressure values were significantly higher during the quiz than at rest for both patient and control groups. There was a significantly higher response for diastolic pressure and a significantly lower response for heart rate in the patient group compared with the control group. In the analysis for occupational status in the entire population, systolic pressure was significantly higher for the executives than for non-executives. Subgroup analyses of patients with angina, hypertension and/or ECG changes (N = 12) revealed a significantly higher diastolic pressure response than found in either the patients without these symptoms (N = 18) or in the controls (N = 30). In comparison to exercise test results, the emotional stress test (quiz) elicited somewhat more PVC's but less ST segment depression. These results support previous reports suggesting that emotional stress testing may be a valid tool in the diagnosis of coronary heart disease and in determining the physiological mechanisms which underlie the association between emotional stress and coronary heart disease.

摘要

在本研究中,30名男性心肌梗死后患者和30名根据年龄和职业匹配的男性对照受试者接受了希弗等人描述的12分钟录音应激测验。在测验前休息时以及测验期间每隔两分钟在实验室环境中监测对情绪刺激的心血管反应(心电图、心率、收缩压和舒张压)。患者组和对照组在测验期间的心率和血压值均显著高于休息时。与对照组相比,患者组的舒张压反应显著更高,心率反应显著更低。在对整个人口中职业状况的分析中,高管的收缩压显著高于非高管。对患有心绞痛、高血压和/或心电图改变的患者(N = 12)进行的亚组分析显示,其舒张压反应显著高于无这些症状的患者(N = 18)或对照组(N = 30)。与运动试验结果相比,情绪应激试验(测验)诱发的室性早搏稍多,但ST段压低较少。这些结果支持了先前的报告,表明情绪应激试验可能是诊断冠心病以及确定情绪应激与冠心病之间关联的生理机制的有效工具。

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