[Distribution and movement of concanavalin A receptors on the surfaces of cells in suspension].

Normal mouse fibroblasts, transformed mouse fibroblasts (L strain), the ascite hepatoma cells (strain 22), the Krebs II ascite cells, and mouse spleen lymphocytes were incubated in suspension in the medium containing concanavalin A which is capable of crosslinking definite groups of surface receptors. Surface-attached ligands were revealed by both direct and indirect immunofluorescent methods. The incubation of all the cell types with that ligand-induced patching rather than capping of corresponding surface receptors. Colcemid had no effect on the ligand-induced redistribution of receptors.