Dan M, Bar-Meir S, Jedwab M, Shibolet S
Arch Intern Med. 1982 Jan;142(1):148-9.
Documented typhoid fever in a 26-year-old patient was complicated by acute hepatitis with unusually profound jaundice. Liver biopsy revealed focal cell necrosis, mononuclear cell infiltration. Kupffer cell proliferation, and mild cholestasis. Immunofluorescent studies of the liver biopsy revealed deposits of IgG, IgA, IgM, and C3 in the bile canaliculi, suggesting a role for damage by immune complexes in typhoid hepatitis.
一名26岁的伤寒热确诊患者并发急性肝炎，黄疸异常严重。肝脏活检显示局灶性细胞坏死、单核细胞浸润、库普弗细胞增生和轻度胆汁淤积。肝脏活检的免疫荧光研究显示，胆小管中有IgG、IgA、IgM和C3沉积，提示免疫复合物损伤在伤寒性肝炎中起作用。
