Abreo K, Steele T H
Arch Intern Med. 1982 Jan;142(1):163-5.
Two cases of simultaneous medullary sponge and adult polycystic kidney disease developed in siblings. The diagnoses of polycystic kidneys were made by renal ultrasonography and medullary sponge kidney was diagnosed roentgenographically. The family history was markedly positive for "cystic" disease. Medullary sponge kidney might be a precursor of polycystic kidney disease in some instances, or, more likely, this represents two separate afflictions occurring in the same individuals. When large medullary sponge kidneys are encountered, the possibility of concomitant polycystic kidney disease should be entertained and investigated with a sonogram. While the prognosis of isolated sponge kidney is excellent, polycystic kidney disease eventually leads to hypertension and renal failure.
一对兄弟姐妹同时患髓质海绵肾和成人多囊肾病。多囊肾的诊断通过肾脏超声检查做出，髓质海绵肾通过X线检查确诊。家族史显示“囊性”疾病呈明显阳性。在某些情况下，髓质海绵肾可能是多囊肾病的先兆，或者更有可能的是，这代表了同一患者身上发生的两种独立疾病。当遇到较大的髓质海绵肾时，应考虑合并多囊肾病的可能性，并通过超声检查进行排查。虽然孤立性海绵肾的预后良好，但多囊肾病最终会导致高血压和肾衰竭。
