Dunnick N R, Doppman J L, Gill J R, Strott C A, Keiser H R, Brennan M F
Radiology. 1982 Feb;142(2):429-33. doi: 10.1148/radiology.142.2.7054832.
Fifty-eight patients with functional lesions of the adrenal gland underwent radiographic evaluation. Twenty-eight patients had primary aldosteronism (Conn syndrome), 20 had Cushing syndrome, and 10 had pheochromocytoma. Computed tomography (CT) correctly identified adrenal tumors in 11 (61%) of 18 patients with aldosteronomas, 6 of 6 patients with benign cortisol-producing adrenal tumors, and 5 (83%) of 6 patients with pheochromocytomas. No false-positive diagnoses were encountered among patients with adrenal adenomas. Bilateral adrenal hyperplasia appeared on CT scans as normal or prominent adrenal glands with a normal configuration; however, CT was not able to exclude the presence of small adenomas. Adrenal venous sampling was correct in each case, and reliably distinguished adrenal tumors from hyperplasia. Recurrent pheochromocytomas were the most difficult to localize on CT due to the surgical changes in the region of the adrenals and the frequent extra-adrenal locations.
58例肾上腺功能病变患者接受了影像学评估。28例患者患有原发性醛固酮增多症（Conn综合征），20例患有库欣综合征，10例患有嗜铬细胞瘤。计算机断层扫描（CT）在18例醛固酮瘤患者中的11例（61%）、6例良性分泌皮质醇肾上腺肿瘤患者中的6例以及6例嗜铬细胞瘤患者中的5例（83%）中正确识别出肾上腺肿瘤。肾上腺腺瘤患者中未出现假阳性诊断。双侧肾上腺增生在CT扫描上表现为肾上腺正常或增大且形态正常；然而，CT无法排除小腺瘤的存在。肾上腺静脉采血在每种情况下都是正确的，并且能够可靠地将肾上腺肿瘤与增生区分开来。由于肾上腺区域的手术改变以及嗜铬细胞瘤常位于肾上腺外，复发性嗜铬细胞瘤在CT上最难定位。
