Oh C, Lee C, Jacobson J H
Surgery. 1982 Jan;91(1):49-51.
Twenty-eight patients with necrotizing fasciitis of the perineum were treated at the Mount Sinai Medical Center from 1971 to 1979. Ten of the 28 died of the disease, for a mortality rate of 36%. The mortality rate was even higher when the lesion was located in the perianal area and associated with diabetes mellitus and delayed surgical intervention. Necrotizing fasciitis is a rare disease that involves both superficial and deep fascia. It begins with fascial necrosis at onset and rapidly progresses to surrounding fascial planes, eventually involving overlying skin and underlying muscle. Evidence proves that it is not the result of abscess, but primarily originates from fascia and is devoid of frank pus in the well-formed pyogenic abscess cavity. If one observes dark brown necrotic turbid fluid and fails to see frank pus, the disease should be treated as necrotizing fasciitis by complete surgical removal of all necrotic tissue until the normal plane is reached.
1971年至1979年期间,西奈山医疗中心共收治了28例会阴坏死性筋膜炎患者。28例中有10例死于该病,死亡率为36%。当病变位于肛周区域并伴有糖尿病及手术干预延迟时,死亡率更高。坏死性筋膜炎是一种罕见疾病,累及浅筋膜和深筋膜。发病时始于筋膜坏死,并迅速蔓延至周围筋膜平面,最终累及上方皮肤和下方肌肉。有证据表明,它并非脓肿所致,而是主要起源于筋膜,在形成的化脓性脓肿腔内并无明显脓液。如果观察到暗褐色坏死浑浊液体且未见明显脓液,则应将该病视为坏死性筋膜炎,通过彻底手术切除所有坏死组织直至达到正常平面来进行治疗。