Nair C K, Sketch M H, Desai R, Mohiuddin S M, Runco V
Am Heart J. 1982 Feb;103(2):226-9. doi: 10.1016/0002-8703(82)90496-3.
Mitral anular calcification (MAC) is associated with high frequency of conduction defects. To delineate this association in patients with symptomatic bradyarrhythmias, 68 consecutive patients requiring pacemakers (group I) and 56 matched controls (group II) were studied. The patients comprised 41 men and 27 women, whose ages ranged from 24 to 92 years (mean 68). The control group consisted of 56 subjects without bradyarrhythmias, whose ages ranged from 30 to 86 years (mean 70); there were 36 men and 20 women. MAC was detected in 59 patients (87%) with symptomatic bradyarrhythmias compared with 8 subjects (14%) in the control group. In group I, 15 patients (22%) had complete atrioventricular block, 23 patients (34%) had atrial fibrillation with slow ventricular response, and 30 patients (44%) had intermittent sinus arrest. The incidence of MAC was similar among these subgroups (93%, 83%, and 87%, respectively). Thus the present study confirms the strong association of MAC with symptomatic bradyarrhythmias.
二尖瓣环钙化（MAC）与传导缺陷的高发生率相关。为了明确有症状的缓慢性心律失常患者中的这种关联，我们对68例连续需要起搏器治疗的患者（I组）和56例匹配的对照组（II组）进行了研究。患者包括41名男性和27名女性，年龄范围为24至92岁（平均68岁）。对照组由56名无缓慢性心律失常的受试者组成，年龄范围为30至86岁（平均70岁）；其中有36名男性和20名女性。有症状的缓慢性心律失常患者中有59例（87%）检测到MAC，而对照组中为8例（14%）。在I组中，15例患者（22%）发生完全性房室传导阻滞，23例患者（34%）发生伴有缓慢心室反应的心房颤动，30例患者（44%）发生间歇性窦性停搏。这些亚组中MAC的发生率相似（分别为93%、83%和87%）。因此，本研究证实了MAC与有症状的缓慢性心律失常之间的密切关联。
