Conn E H, Williams R S, Wallace A G
Am J Cardiol. 1982 Feb 1;49(2):296-300. doi: 10.1016/0002-9149(82)90504-5.
The ability of patients with severely impaired left ventricle function to perform short-term exercise and to participate in a cardiac rehabilitation program and attain physical training effects was evaluated. Treadmill exercise tests were performed before and after physical conditioning in 10 patients with a prior myocardial infarction and a left ventricular ejection fraction at rest of less than 27 percent (range 13 to 26) determined by radionuclide angiography. All patients participated in a supervised exercise program with a follow-up period of 4 to 37 (mean 12.7) months. Baseline exercise capacity showed marked variability, ranging from 4.5 to 9.4 (mean 7.0 +/- 1.9) METS, and improved to 5.5 to 14 (mean 8.5 +/- 2.9) METS after conditioning (p = 0.05). The oxygen pulse (maximal oxygen uptake/maximal heart rate) before and after conditioning was used to assess a training effect and increased significantly from 12.8 +/- 2.0 to 15.7 +/- 3.2 ml/beta (p less than 0.01). There was no exercise-related morbidity or mortality, although two patients died during the study period. It is concluded that selected patients with severely imparied left ventricular function can safely participate in a conditioning program and achieve cardiovascular training effects.
对左心室功能严重受损的患者进行短期运动、参与心脏康复计划并获得体育锻炼效果的能力进行了评估。对10例既往有心肌梗死且静息左心室射血分数经放射性核素血管造影测定小于27%（范围为13%至26%）的患者，在体能训练前后进行了跑步机运动测试。所有患者均参加了一项有监督的运动计划，随访期为4至37个月（平均12.7个月）。基线运动能力显示出显著差异，范围为4.5至9.4（平均7.0±1.9）代谢当量，训练后提高到5.5至14（平均8.5±2.9）代谢当量（p = 0.05）。训练前后的氧脉搏（最大摄氧量/最大心率）用于评估训练效果，从12.8±2.0显著增加到15.7±3.2毫升/次（p＜0.01）。尽管有两名患者在研究期间死亡，但未出现与运动相关的发病率或死亡率。结论是，选定的左心室功能严重受损的患者可以安全地参与体能训练计划并获得心血管训练效果。
