Siregar H, Chou C C
Am J Physiol. 1982 Jan;242(1):G27-31. doi: 10.1152/ajpgi.1982.242.1.G27.
The relative contribution of dietary fat, protein, carbohydrate, and ethanol to postprandial intestinal hyperemia was assessed by comparing the vascular and metabolic effects of luminal placement of various solutions prepared from standard high -fat, high-protein, and high-carbohydrate test diets, corn oil, and ethanol in the jejunum of anesthetized dogs. The high-fat diet (45% fat, 18% protein, 29% carbohydrate) produced the greatest hyperemia (+30.4% of control), followed by high-protein (22% fat, 64% protein, 4% carbohydrate) (+24.1%) and high-carbohydrate (8% fat, 18% protein, 68% carbohydrate) (+18.2%) diets. When the fat content of the high-carbohydrate diet was raised to equal that of the high-protein diet, the two diets produced the same degree of hyperemia. All three diets produced a significantly greater hyperemia than the solutions containing the same amount of fat. All these dietary solutions increased intestinal oxygen consumption. Ethanol, however, increased blood flow without altering oxygen consumption. Thus, on weight basis, fat produces the greatest hyperemia, but the contribution of protein and carbohydrate to postprandial intestinal hyperemia cannot be considered as insignificant. The hyperemia results from a synergistic effect of all three dietary components.
通过比较由标准高脂、高蛋白和高碳水化合物试验饮食、玉米油和乙醇制备的各种溶液在麻醉犬空肠内的血管和代谢效应，评估膳食脂肪、蛋白质、碳水化合物和乙醇对餐后肠充血的相对贡献。高脂饮食（45%脂肪、18%蛋白质、29%碳水化合物）引起的充血最为显著（+30.4%对照），其次是高蛋白饮食（22%脂肪、64%蛋白质、4%碳水化合物）（+24.1%）和高碳水化合物饮食（8%脂肪、18%蛋白质、68%碳水化合物）（+18.2%）。当高碳水化合物饮食的脂肪含量提高到与高蛋白饮食相当时，这两种饮食产生的充血程度相同。所有三种饮食产生的充血都明显大于含有相同量脂肪的溶液。所有这些膳食溶液均增加了肠道耗氧量。然而，乙醇增加了血流量但未改变耗氧量。因此，以重量计，脂肪产生的充血最为显著，但蛋白质和碳水化合物对餐后肠充血的贡献也不可忽视。充血是由所有三种膳食成分的协同作用引起的。
