Chiari R, Gilch W
Urologe A. 1978 Sep;17(5):303-7.
The significance for the results of external ureterovesicoplasty of damaging the vesical mucosa was investigated in rabbits. On one side, the submucosal ureter was lengthened by myotomy, and on the other side, an additional incision of the mucosa caused the ureter to be shifted intravesically. In 10 animals, results were symmetric; in 7 cases, stasis occurred on the side of the sunken ureter; 2 animals showed marked hydronephrosis on the Grégoir side. Increased mobility and thereby kinking of the intravesical ureter and inflammatory reaction on temporary leakage of urine are shown to be the causes of worse results following mucosa leakage. As consequence of the study importance of careful closure of any mucosal defect occurring during Grégoir operation is stressed.
在兔子身上研究了损伤膀胱黏膜对输尿管膀胱外成形术结果的影响。一侧通过肌切开术延长黏膜下输尿管，另一侧额外切开黏膜使输尿管在膀胱内移位。10只动物的结果是对称的；7例中，输尿管下陷侧出现了淤积；2只动物在Grégoir侧出现了明显的肾积水。膀胱内输尿管活动度增加进而扭结以及尿液暂时渗漏引起的炎症反应被证明是黏膜渗漏后结果较差的原因。作为该研究的结果，强调了在Grégoir手术过程中仔细闭合任何出现的黏膜缺损的重要性。
