Howie A J
Clin Otolaryngol Allied Sci. 1982 Feb;7(1):35-44. doi: 10.1111/j.1365-2273.1982.tb01559.x.
The material lying within the crypts of 11 human palatine tonsils was studied by scanning and transmission electron microscopy. There was a mixture of desquamated epithelial cells and various non-epithelial cells, mainly lymphocytes, with some mononuclear phagocytes and plasma cells, and a few erythrocytes, neutrophil leucocytes and mast cells. Many of the cells were degenerating and there was a great deal of cellular debris. The non-epithelial cells seemed to have entered the crypts from the lining epithelium, probably by being caught up between superficial squamous epithelial cells as they sloughed into the lumen. The widespread cellular degeneration in the crypts suggested that the cells were being lost from the body and that they had no further immunological or phagocytic function. This also suggested that the first level of defence mechanisms of the tonsil was in the epithelium, not in the crypt lumen.
采用扫描电子显微镜和透射电子显微镜对11例人类腭扁桃体隐窝内的物质进行了研究。其中有脱落的上皮细胞和各种非上皮细胞的混合物，主要是淋巴细胞，还有一些单核吞噬细胞和浆细胞，以及少量红细胞、中性粒细胞和肥大细胞。许多细胞正在退化，并有大量细胞碎片。非上皮细胞似乎是从衬里上皮进入隐窝的，可能是在表层鳞状上皮细胞脱落进入管腔时夹在其中而进入的。隐窝内广泛的细胞退化表明这些细胞正在从体内流失，并且它们不再具有进一步的免疫或吞噬功能。这也表明扁桃体防御机制的第一层级位于上皮，而非隐窝管腔。
