Schmaltz A A, Irion K M, Graneis R, Epple E, Steil E, Bleicher W, Frey R
Herz. 1982 Feb;7(1):50-6.
Twenty-nine children with echocardiographically-proven mitral valve prolapse (MVP) were studied by means of exercise-ECG testing, and continuous ECG monitoring. ECG's were stored on tape and compared with those of 20 healthy children. The frequency of supra- and ventricular premature beats (VPB) and the response of heart rate and RR intervals over the length of time ("tachogram") were graphed and analyzed by various algorithms. Of the children with MVP, one required treatment for his arrhythmia. A total of 16 children with MVP ( = 55%) had various rhythm disturbances. VPB's were observed in one child in the routine ECG, in four children during exercise testing, and in nine only during continuous ECG monitoring, whereas only 9% of the healthy children were found to display VPB's. Differences could also be seen in the tachogram readings: 22 ( = 76%) MVP children were characterized by a wide variation of RR intervals, suggesting a pronounced sympathetic reactivity, twelve ( = 60%) healthy and six ( = 23%) MVP children showed a narrow, oscillating tachogram trace. Although the syndrome is already present in childhood, it must be seen as progredient, manifesting itself in the frequency and gravity of arrhythmias.
对29名经超声心动图证实患有二尖瓣脱垂（MVP）的儿童进行了运动心电图测试和连续心电图监测研究。心电图被记录在磁带上，并与20名健康儿童的心电图进行比较。通过各种算法绘制并分析了室上性和室性早搏（VPB）的频率以及心率和RR间期在一段时间内的反应（“心动图”）。在患有MVP的儿童中，有一名因心律失常需要治疗。共有16名患有MVP的儿童（占55%）出现了各种节律紊乱。在常规心电图中，有一名儿童观察到VPB，在运动测试中有四名儿童观察到VPB，只有在连续心电图监测期间有九名儿童观察到VPB，而只有9%的健康儿童被发现有VPB。在心动图读数中也可以看到差异：22名（占76%）患有MVP的儿童的特点是RR间期变化很大，表明有明显的交感神经反应性，12名（占60%）健康儿童和6名（占23%）患有MVP的儿童的心动图轨迹狭窄且有波动。尽管该综合征在儿童期就已存在，但必须将其视为进行性的，表现为心律失常的频率和严重程度。
