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沙特国民常见血液学和生化参数参考值的一项初步研究。

A pilot study of the reference values for the commoner haematological and biochemical parameters in Saudi nationals.

作者信息

Scott T G

出版信息

J Clin Pathol. 1982 Jan;35(1):69-73. doi: 10.1136/jcp.35.1.69.

Abstract

A study of 16 haematological and 24 biochemical parameters in healthy, adult, male, volunteer Saudi blood donors was made, and enabled a preliminary determination of the reference values for these parameters to be made for Saudi Arabia. Statistically significant low means were observed for all the haematological parameters except the mean corpuscular haemoglobin concentration which was raised above Western levels and the mean corpuscular haemoglobin which was normal. A low total leucocyte count was seen to be due largely to a low neutrophil count, but accompanied by a raised lymphocyte count. The main biochemical differences were raised concentrations of serum albumin, alkaline phosphatase, conjugated bilirubin, aspartate aminotransferase, "liver" lactate dehydrogenase and alanine aminotransferase. Decreased concentrations of serum globulin, unconjugated bilirubin and calcium were also found. These changes are discussed in relation to putative endemic disease, ethnic origins and environmental factors.

摘要

对沙特健康成年男性志愿献血者的16项血液学参数和24项生化参数进行了研究,从而初步确定了这些参数在沙特阿拉伯的参考值。除平均红细胞血红蛋白浓度高于西方水平且平均红细胞血红蛋白正常外,所有血液学参数的均值均呈现出具有统计学意义的偏低。低白细胞总数主要是由于中性粒细胞计数低,但同时淋巴细胞计数升高。主要的生化差异在于血清白蛋白、碱性磷酸酶、结合胆红素、天冬氨酸转氨酶、“肝脏”乳酸脱氢酶和丙氨酸转氨酶的浓度升高。还发现血清球蛋白、非结合胆红素和钙的浓度降低。结合假定的地方病、种族起源和环境因素对这些变化进行了讨论。

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