Riopel L, Fouron J C, Bard H
J Pediatr. 1982 Mar;100(3):449-53. doi: 10.1016/s0022-3476(82)80458-7.
Adult and newborn infant blood viscosity have been compared, taking into account not only the hematocrit, but also the type of red blood cells (fetal or adult) in the circulation and the plasma viscosity. At all shear rates studied, the viscosity of the adults' blood was higher than that of the newborn infant. At shear rates of 11.5 and 46 second-1, an increase in the hematocrit influences the viscosity of neonatal and adult blood similarly. At 115 and 230 second-1, the rise in hematocrit was associated with a greater increase in viscosity in the presence of fetal red blood cells, probably because of their lesser deformability. Plasma viscosity was 1.18 +/- 0.17 centipoises in the newborn compared to 1.36 +/- 0.10 in the adult group (P less than 0.001). The relative apparent viscosity (apparent viscosity/plasma viscosity) was higher in the neonate at a hematocrit of 65% (P less than 0.05). In normal conditions, blood viscosity is lower in the neonatal period because of a lower plasma viscosity.
对成人和新生儿的血液粘度进行了比较，不仅考虑了血细胞比容，还考虑了循环中红细胞的类型（胎儿型或成人型）以及血浆粘度。在所研究的所有剪切速率下，成人血液的粘度均高于新生儿。在11.5和46秒-1的剪切速率下，血细胞比容的增加对新生儿和成人血液粘度的影响相似。在115和230秒-1时，在存在胎儿红细胞的情况下，血细胞比容的升高与粘度的更大增加相关，这可能是因为它们的变形性较小。新生儿的血浆粘度为1.18±0.17厘泊，而成人组为1.36±0.10（P<0.001）。在血细胞比容为65%时，新生儿的相对表观粘度（表观粘度/血浆粘度）更高（P<0.05）。在正常情况下，由于血浆粘度较低，新生儿期的血液粘度较低。
