Ramsay R A, Ananth J, Engelsmann F, Krakowski A J, Wittkower E D, Ghadirian A M
J Psychosom Res. 1982;26(1):33-42. doi: 10.1016/0022-3999(82)90060-5.
In order to explore the possibility of a mutually exclusive relationship between schizophrenia and certain psychosomatic disorders, 354 adult schizophrenic patients, both acute and chronic, were studied with regard to lifetime prevalence of peptic ulcer, bronchial asthma, neurodermatitis and rheumatoid arthritis. Significant evidence to support the hypothesis of mutual exclusivity was found only in the case of peptic ulcer in the overall sample. Prevalence was higher in younger, more acute patients than in older, chronic patients, but this finding was difficult to interpret. Parallel enquiry into the prevalence of schizophrenia and the same disorders among close family members of the patients yielded inconclusive results.
为了探究精神分裂症与某些身心疾病之间相互排斥关系的可能性,我们对354名成年精神分裂症患者(包括急性和慢性患者)进行了研究,调查他们患消化性溃疡、支气管哮喘、神经性皮炎和类风湿性关节炎的终生患病率。仅在总体样本中消化性溃疡的情况发现了支持相互排斥假说的重要证据。年轻、急性患者的患病率高于年长、慢性患者,但这一发现难以解释。对患者近亲中精神分裂症及相同疾病患病率的平行调查结果尚无定论。