Dronova L M, Erokhin V N, Belich E I
Vopr Onkol. 1978;24(9):65-71.
Under study was the kinetics of the development in primary passages of AKR leukemia transplanted by different number of cells. The indices of the leukemic process (the spleen, lymph nodes, the liver, thymus, blood leucocytes) vary with time in extreme curves. The leukemia transplantability is reduced from 100% to 24% with lessening of the transplant from 10(4) to 10(1) cells. The latent period duration and the survival of mice are linearly related to the transplanted cells number logarythm.
