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[1977 - 1979年皮埃蒙特医院收治的1258例病毒性肝炎临床流行病学研究]

[Clinico-epidemiologic study on 1258 cases of viral hepatitis admitted to Piedmont hospitals 1977-1979].

作者信息

Soranzo M L, Andreoni M, Bramato C, Casini E, De Bernardis A, Gandini F, Gaydou L, Ricciardiello P T, Traverso A

出版信息

Minerva Med. 1982 Feb 11;73(5):175-80.

PMID:7063134
Abstract

A clinical and epidemiological assessment of 1258 hospital patients in Piedmont in 1977-1979 showed that, at present, the frequency of hepatitis A and B can be regarded as virtually the same, that males are more frequently affected, that AVH A is more frequent in early life, whereas AVH B is significantly more common later, that urban areas are more frequently stricken than rural areas, that AVH A is more common in persons living in groups, whereas AVH B is more frequent among pensioners and the unemployed (the latter being primarily drug-addicts). Patients with AVH A, and hence a minor hepatitic involvement, had shorter hospital stays, while the immune response in both types of hepatitis is characterized by a more frequent increase in gamma-globulins, coupled with arise in IgM levels.

摘要

1977年至1979年对皮埃蒙特地区1258名住院患者进行的临床和流行病学评估显示,目前甲型肝炎和乙型肝炎的发病率几乎相同,男性更易感染,甲型急性病毒性肝炎在早年更为常见,而乙型急性病毒性肝炎在后期明显更为普遍,城市地区比农村地区发病更频繁,甲型急性病毒性肝炎在群居人群中更常见,而乙型急性病毒性肝炎在退休人员和失业者(后者主要是吸毒者)中更频繁。甲型急性病毒性肝炎患者肝脏受累较轻,住院时间较短,而两种肝炎的免疫反应均表现为γ球蛋白更频繁升高,同时IgM水平也升高。

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