Lactic deshydrogenase isoenzymes in the ocular tissues and liquids.

Lactic deshydrogenase isoenzymes in different parts of the ocular tissues and humors were analyzed. An appreciation in crossing of the lactic deshydrogenase concentration was indicated. In the human eye, the largest quantities of lactic deshydrogenase were found in the cornea and in the vitreous and aqueous humors, where isoenzymes 3, 4, and 5 are the most numerous. Lactic deshydrogenase was found in small quantities only in the conjunctiva and in the lacrimal gland. In the bovine eye, the proportion of isoenzymes is different. The chemical constitution of human serum isoenzymes seems to differ from that of the tissues and liquids in the bovine eye (their mobility is different). Therefore, the results obtained with bovine eyes cannot be applied to human eyes. The largest quantity of lacrimal lactic deshydrogenase isoenzymes comes from the cornea, any recent corneal lesion causing an increase in isoenzyme 4.