Dixsaut G, Teillet F, Dana M, Miot C, Catherine N, Teillet-Thiebaud F
Nouv Presse Med. 1982 Feb 6;11(6):429-32.
In 15 patients with mediastinal Hodgkin's disease treated with chemotherapy followed by mantle-field irradiation respiratory function tests performed before and after irradiation showed a decrease in vital capacity and FEV1 as compared with pretreatment values. The decrease was maximum at 4 months and regressed over one year. No significant changes were observed in blood gas measurements. Respiratory symptoms, which were frequent after irradiation, almost completely disappeared within one year. The therapeutic combination had no cumulative adverse effect on respiratory function.
15例纵隔霍奇金病患者接受化疗后再行斗篷野照射，照射前后进行的呼吸功能测试显示，与治疗前相比，肺活量和第一秒用力呼气量下降。下降在4个月时最大，并在1年内逐渐恢复。血气测量未观察到显著变化。照射后常见的呼吸道症状在1年内几乎完全消失。这种治疗组合对呼吸功能没有累积不良影响。
