Polk O D, Kletter G G, Smith J, Castro O
South Med J. 1982 Mar;75(3):374-5. doi: 10.1097/00007611-198203000-00036.
We have described a case of thrombocytopenic purpura caused by methyldopa. A methyldopa-dependent antiplatelet antibody as the mechanism of the patient's thrombopenia was suggested by a positive clot retraction inhibition test. This simple in vitro test should be done more often in suspected cases of drug-induced thrombocytopenia.
我们描述了一例由甲基多巴引起的血小板减少性紫癜病例。凝块回缩抑制试验呈阳性,提示存在甲基多巴依赖性抗血小板抗体,这是该患者血小板减少的机制。对于疑似药物性血小板减少症的病例,应更频繁地进行这种简单的体外试验。