Santangelo M L, Usberti M, Di Salvo E, Belli G, Romano G, Sassaroli C, Zotti G
Surg Gynecol Obstet. 1982 Mar;154(3):372-4.
Subsequent to the earthquake which occurred in Southern Italy in November 1980, 19 patients were admitted to the University of Naples--II Medical School with crush syndrome. Clinical and biochemical studies were carried out in eight of them. The most interesting observation was the inconstant relation between the type of lesion and the clinical course, leading to the assumption of two diverse physiopathologic mechanisms--one for crush and the other for compression. The timely recognition of the two syndromes is difficult; an elevated creatine-creatinine ratio has been found in those patients with an irreversible crush syndrome. We believe this to be the only element which would permit a prompt distinction between the two pathologic states and which would provide an indication for early, life-saving amputation.
1980年11月意大利南部发生地震后，19名挤压综合征患者被收治入那不勒斯大学第二医学院。对其中8名患者进行了临床和生化研究。最有趣的观察结果是损伤类型与临床病程之间的关系不稳定，由此推测存在两种不同的病理生理机制——一种是挤压机制，另一种是压迫机制。及时识别这两种综合征很困难；在患有不可逆挤压综合征的患者中发现肌酸-肌酐比值升高。我们认为这是唯一能够迅速区分这两种病理状态并为早期挽救生命的截肢提供指征的因素。
