Galluzzo T S, Ts'ao C H
Thromb Res. 1982 Feb 1;25(3):237-43. doi: 10.1016/0049-3848(82)90243-2.
Heparin levels in 76 heparinized patient plasma samples were determined with a thrombin-sensitive fluorogenic substrate. Results were compared with heparin values derived from an activated partial thromboplastin time test. The correlation of heparin concentrations obtained by these two methods was poor (r = 0.56). The amidolytic assay gave higher heparin values than the clotting method. The discrepancy is attributed to factors inherent to the methodology of these assay systems.
采用凝血酶敏感的荧光底物测定了76份肝素化患者血浆样本中的肝素水平。将结果与活化部分凝血活酶时间试验得出的肝素值进行了比较。这两种方法测得的肝素浓度相关性较差（r = 0.56）。酰胺水解测定法得出的肝素值高于凝血法。这种差异归因于这些测定系统方法本身固有的因素。
