Baskakov V P, Tsvelëv Iu V
Vopr Onkol. 1982;28(3):45-51.
Such features as single-phase cycling, endocrine infertility, endometriosis concomitant endometrial hyperplasia, endometrial carcinoma and endometriosis with concomitant uterine myoma and proliferative processes in the mammary glands as well as hormono-metabolic disorders frequently occur both in endometriosis and endometrial carcinoma and, therefore, suggest that pathogenesis of these hormone-dependent diseases has something in common. It was established experimentally that the likelihood of proliferation development and malignancy in the endometrium is great, when it is dislocated and, particularly, when hormonal disorders occur. An autoimmune nature of endometriosis is suggested. The similarity and differences in diagnosis of endometriosis and some types of cancer as well as common principles of treatment of the diseases are discussed. It is recommended in conclusion that patients with endometriosis of the uterus, ovary and other sites should be referred to a group at high risk for cancer.
诸如单相循环、内分泌性不孕、子宫内膜异位症合并子宫内膜增生、子宫内膜癌以及子宫内膜异位症合并子宫肌瘤和乳腺增生性病变等特征，以及激素代谢紊乱，在子宫内膜异位症和子宫内膜癌中都经常出现，因此表明这些激素依赖性疾病的发病机制有某些共同之处。实验证明，当子宫内膜移位时，尤其是发生激素紊乱时，子宫内膜发生增殖和恶变的可能性很大。有人提出子宫内膜异位症具有自身免疫性质。文中讨论了子宫内膜异位症与某些类型癌症在诊断上的异同以及这些疾病的共同治疗原则。最后建议，患有子宫、卵巢及其他部位子宫内膜异位症的患者应被归为癌症高危人群。
