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强烈听觉刺激后鸡基底乳头毛细胞损失模式。频率组织。

Patterns of hair cell loss in chick basilar papilla after intense auditory stimulation. Frequency organization.

作者信息

Ryals B M, Rubel E W

出版信息

Acta Otolaryngol. 1982;93(1-6):205-10. doi: 10.3109/00016488209130873.

DOI:10.3109/00016488209130873
PMID:7064706
Abstract

Ten-day-old chicks were continuously exposed to pure tones (500, 1 500, or 3 000 Hz) at 125 dB SPL for 12 hours and sacrificed 10 days after exposure. The basilar papillae were embedded in plastic, sectioned and hair cells were counted at 100-mum intervals throughout the length of the papilla. The position of hair cell loss along the basilar membrane varied systematically as a log-linear function with the frequency of stimulation. This systematic relationship was used to predict the frequency organization of the chick basilar papilla. It is concluded that although the avian basilar papilla differs greatly in morphological detail from the mammalian cochlea, its response to intense acoustic stimulation is quite similar.

摘要

10日龄雏鸡连续12小时暴露于125分贝声压级的纯音(500、1500或3000赫兹)下,暴露后10天处死。将基底乳头嵌入塑料中,切片,并在乳头全长以100微米的间隔计数毛细胞。沿基底膜的毛细胞损失位置随刺激频率呈对数线性函数系统变化。这种系统关系被用于预测雏鸡基底乳头的频率组织。结论是,尽管鸟类基底乳头在形态细节上与哺乳动物耳蜗有很大差异,但其对强烈声刺激的反应相当相似。

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