Kozarek R A, Sanowski R A
Am J Gastroenterol. 1982 Jan;77(1):5-8.
Although esophageal strictures with attendant malignant degeneration are well known sequelae of caustic ingestion, fixed pharyngeal structural lesions and development of oral leukoplakia are not well appreciated consequences of such ingestion. We present a patient 12 yr after lye ingestion who displayed rapidly progressive dysphagia suggestive of esophageal carcinoma. Instead, adhesions bisecting the cricopharyngeal inlet and an upper esophageal stricture were found endoscopically. In addition, an area of hypopharyngeal leukoplakia with marked acanthosis, parakeratosis, and dysplasia was noted and resected. The management of this patient's dysphagia and subsequent follow-up for his potentially precancerous oral lesion form the basis of this report.
尽管腐蚀性物质摄入后食管狭窄伴恶性变是众所周知的后遗症，但固定性咽部结构病变和口腔白斑的发生却未得到充分认识。我们报告1例患者，在摄入碱液12年后出现迅速进展的吞咽困难，提示食管癌。然而，内镜检查发现环状咽入口被粘连平分，并有食管上段狭窄。此外，发现下咽有一白斑区域，伴有明显棘皮症、不全角化和发育异常，予以切除。本文报道了该患者吞咽困难的处理方法及对其潜在癌前口腔病变的后续随访情况。
